| Set | Manufacturer | Year | Category | |
| American Pie | Topps | 2001 | Movie | |
| American Pride | Inkworks | 2001 | History & Nostalgia | |
| Andromeda (season 1) | Inkworks | 2001 | TV | |
| Aphrodite IX Dynamic Chrome | Dynamic Forces | 2001 | Other Action Comics | |
| Army National Guard (series 1) | ARNB | 2001 | History & Nostalgia | |
| Babylon 5 Archive, Women of | Rittenhouse Archives | 2001 | Babylon | |
| Beetlejuice 2001 | NECA / Warner Brothers, Inc. | 2001 | Movie | |
| Betty Boop | Dart Flipcards, Inc. | 2001 | Cartoon | |
| Black Scorpion | Rittenhouse Archives | 2001 | Movie | |
| Black Scorpion Preview Set | Rittenhouse Archives | 2001 | Movie | |
| Bubblegum | Artbox Entertainment | 2001 | ||
| Buffy The Vampire Slayer (series 5) | Inkworks | 2001 | Buffy | |
| Buffy the Vampire Slayer Top Trumps | Winning Moves | 2001 | Buffy | |
| Buffy, The Story So Far | iKon Collectibles | 2001 | Buffy | |
| Captain Scarlet | Cards, Inc. | 2001 | Movie | |
| Celebrate America: 50 States (series 2) | Doral | 2001 | History & Nostalgia | |
| Celebrate America: Snapshots of the Century | Doral | 2001 | History & Nostalgia | |
| Coaster Cards: Inaugural Issue | NostalgiCards | 2001 | Novelty | |
| Darkchylde | Dynamic Forces | 2001 | ||
| Dexter's Laboratory | Artbox Entertainment | 2001 | Anime Manga | |
| Disney Posters (Animation) | Disney | 2001 | Disney & Animated Movies | |
| Disney Signature Series | Disney | 2001 | Disney & Animated Movies | |
| Doctor Who Definitive 2 | Strictly Ink | 2001 | TV | |
| Dragonball Z (series 2) | Artbox Entertainment | 2001 | Anime Manga | |
| Dragonball Z (series 3) | Artbox Entertainment | 2001 | Anime Manga | |
| Enduring Freedom | Topps | 2001 | History & Nostalgia | |
| Fairy Tale Freaks | Burger King | 2001 | Movie | |
| Fantasy Art of Michael Bruinsma | NostalgiCards | 2001 | Art | |
| Farscape (season 2) | Rittenhouse Archives | 2001 | TV | |
| Farscape Crichton Set | Rittenhouse Archives | 2001 | TV | |
| Farscape In Motion | Rittenhouse Archives | 2001 | TV | |
| Fathom | Dynamic Forces | 2001 | Other Action Comics | |
| Fathom Preium Preview | Dynamic Forces | 2001 | Other Action Comics | |
| Final Fantasy | Comic Images | 2001 | Movie | |
| Final Fantasy Art Museum (3rd edition) | Square | 2001 | Anime / Manga | |
| Final Fantasy Art Museum (4th edition) | Square | 2001 | Anime / Manga | |
| First Wave 6 Card Preview Set | Rittenhouse Archives | 2001 | TV | |
| Ghost of Mars (series 1) | Screen Gems | 2001 | Movie | |
| Ghost of Mars (series 2) | Screen Gems | 2001 | Movie | |
| Gumby Preview Set | Toon's Station | 2001 | TV | |
| Gundam: Endless Waltz | Upper Deck | 2001 | Anime / Manga | |
| Harry Potter and the Sorcerer's Stone | Wizards of the Coast | 2001 | Harry Potter | § |
| Henchmen of Horror | Goodstuff Cards | 2001 | Movie | |
| Hercules 9-Card Preview Set |